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Krṣṇa, the Supreme Personality of Godhead
and certainly they have no interest in material activities for elevation to the heavenly planets for sense gratification. Pure devotees seek only the association of  paramahaṁsas , or great liberated devotees, so that they can continually hear and chant about Your glories. For this purpose the pure devotees are prepared to sacrifice all comforts of life, even giving up the material comforts of family life and so-called society, friendship and love. Those who have tasted the nectar of devotion by relishing the transcendental vibration of chanting Your glories, Hare Krṣṇa, Hare Krṣṇa, Krṣṇa Krṣṇa, Hare Hare/ Hare Rāma, Hare Rāma, Rāma Rāma, Hare Hare, do not care for any other spiritual bliss or for material comforts, which appear to the pure devotee to be less important than the straw in the street.”
The personified  Vedas  continued: “Dear Lord, when a person is able to purify his mind, senses and intelligence by engaging himself in devotional service in full Krṣṇa consciousness, his mind becomes his friend. Otherwise, his mind is always his enemy. When the mind is engaged in devotional service of the Lord, it becomes the intimate friend of the living entity because the mind can then think of the Supreme Lord always. Your Lordship is eternally dear to the living entity, so when the mind is engaged in thought of You, one immediately feels the great satisfaction for which he has been hankering life after life. When one’s mind is thus fixed on the lotus feet of the Supreme Personality of Godhead, one does not take to any kind of inferior worship or inferior process of self-realization. By attempting to worship a demigod or by taking to any other process of self-realization, the living entity becomes a victim of the cycle of birth and death, and no one can estimate how much the living entity becomes degraded by entering the abominable species of life such as the cats and dogs.”
Śrī Narottama dāsa Thākur has sung that persons who do not take to devotional service of the Lord but are attracted to the process of philosophical speculation and fruitive activities drink the poisonous results of such actions. Such persons are forced to take birth in different species of life and are forced to adopt obnoxious practices like meat-eating and intoxication. Materialistic persons generally worship the transient material body and forget the welfare of the spirit soul within the body. Some take shelter of materialistic science to improve bodily comforts, and some take to the worship of demigods in order to be promoted to the heavenly planets. Their goal in life is to make the material body comfortable while forgetting the interest of the spirit soul. Such persons are described in the Vedic literature as suicidal because attachment for the material body and its comforts forces the living entity to wander through the process of birth