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Perfect Questions, Perfect Answers
perfection. That is stated in  Bhagavad-gītā :
sve sve karmaṇy abhirataḥ saṁsiddhiṁ labhate naraḥ
“By following his qualities of work, every man can become perfect.” Complete perfection.  Saṁsiddhi .  Siddhi  is perfection. That is Brahman realization, spiritual realization. And  saṁsiddhi  means devotion, which comes after Brahman realization.
BOB:  Could you just say that last thing again please?
ŚRĪLA PRABHUPĀDA:   Saṁsiddhi .
BOB:  Yes.
ŚRĪLA PRABHUPĀDA:   Saṁ  means complete.
BOB:  Yes.
ŚRĪLA PRABHUPĀDA:  And  siddhi  means perfection. In the  Bhagavad-gītā  it is stated that one who goes back to home, back to Godhead, has attained the complete perfection. So perfection comes when one realizes that he is not this body; he is spirit soul.  Brahma-bhūta —that is called Brahman realization. That is perfection. And  saṁsiddhi  comes after Brahman realization, when one engages in devotional service. Therefore if one is already engaged in devotional service, it is to be understood that Brahman realization is there. Therefore it is called  saṁsiddhi .
BOB:  I ask you this very humbly, but do you feel diseases and sickness?
ŚRĪLA PRABHUPĀDA:  Hm-m?
BOB:  Do you personally feel disease and sickness?
ŚRĪLA PRABHUPĀDA:  Yes.
BOB:  Is this a result of your past  karma ?
ŚRĪLA PRABHUPĀDA:  Yes.