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THE SCIENCE OF SELF-REALIZATION
The culture of  vidyā , or transcendental knowledge, is essential for the human being, otherwise the culture of  avidyā , or nescience, binds him to conditional existence on the material platform. Materialistic existence means the pursuit or culture of sense gratification, and this kind of knowledge of sense gratification ( avidyā ) means advancement of repeated birth and death. Those who are absorbed in such knowledge cannot learn any lesson from the laws of nature, and they do the same things over repeatedly, being enamored of the beauty of illusory things.  Vidyā , or factual knowledge, on the other hand, means to know thoroughly the process of nescient activities while at the same time culturing transcendental science and thereby undeviatingly following the path of liberation.
Liberation is the enjoyment of the full blessings of immortality. This immortality is enjoyed in the eternal kingdom of God ( sambhūty-amṛtam aśnute ), the region of the Supreme Personality of Godhead, and is the result obtained by worshiping the Supreme Lord, the cause of all causes,  sambhavāt . So in this way real knowledge,  vidyā , means to worship the Supreme Personality of Godhead,  Kṛṣṇa ; that is  jñāna-yajñena , the worship of knowledge.
This  jñāna-yajñena  . . .  yajanto mām  is the perfection of knowledge, as stated in the  Bhagavad-gītā  [7.19]:
bahūnām janmanām ante jñānavān mām prapadyate vāsudevaḥ sarvam iti sa mahātmā sudurlabhaḥ
“After many births and deaths, he who is actually in knowledge surrenders unto Me [ Kṛṣṇa ], knowing Me to be the cause of all causes, and all that is. Such a great soul is very rare.”
If one has not yet come to this conclusion of knowledge and simply indulges in dry speculation without  Kṛṣṇa , then his hard speculative labor is something like beating empty husks of grain. The unhulled rice and the empty husks of rice look very much the same. One who knows how to get the grain out of the unhulled rice is wise, but one who beats on the empty husk, thinking to get some result, is simply wasting his labor uselessly. Similarly, if one studies the  Vedas  without finding the goal of the  Vedas ,  Kṛṣṇa , he simply wastes his valuable time.
So to cultivate knowledge for worshiping  Kṛṣṇa  culminates after many, many births and deaths when one actually becomes wise. When one becomes wise in this way, he surrenders to  Kṛṣṇa , recognizing Him at