Text 18]
Conversation Between Manu and Kardama
821
one should give up the conditional life of this material world and the association of so-called civilized human beings who are simply following, in a polished way, the same stereotyped principles of eating, sleeping, defending and mating. Chanting and hearing of the glories of the Lord is described here as  tvad-guṇa-vāda-sīdhu . Only by drinking the nectar of chanting and hearing the pastimes of the Lord can one forget the intoxication of material existence.
TEXT 18
न तेऽजराक्षभ्रमिरायुरेषां 
    त्रयोदशारं त्रिशतं षष्टिपर्व । 
    षण्नेम्यनन्तच्छदि यत्त्रिणामि 
    करालस्रोतो जगदाच्छिद्य धावत् ॥१८॥
na te 'jarākṣa-bhramir āyur eṣām 
    trayodaśāram tri-śatam ṣaṣṭi-parva 
    ṣaṇ-nemy ananta-cchadi yat tri-ṇābhi 
    karāla-sroto jagad ācchidya dhāvat
na—not; te—Your; ajara—of imperishable Brahman; akṣa—on the axle; bhramiḥ—rotating; āyuḥ—span of life; eṣām—of the devotees; trayodaśa—thirteen; aram—spokes; tri-śatam—three hundred; ṣaṣṭi—sixty; parva—functions; ṣaṣ—six; nemi—rims; ananta—innumerable; chadi—leaves; yat—which; tri—three; nābhi—naves; karāla-srotaḥ—with tremendous velocity; jagat—the universe; ācchidya—cutting short; dhāvat—running.
TRANSLATION
Your wheel, which has three naves, rotates around the axis of the imperishable Brahman. It has thirteen spokes, 360 joints, six rims and numberless leaves carved upon it. Though its revolution cuts short the life span of the entire creation, this wheel of tremendous velocity cannot touch the life span of the devotees of the Lord.
PURPORT
The time factor cannot affect the span of life of the devotees. In  Bhagavad-gītā  it is stated that a little execution of devotional service saves one from the greatest danger. The greatest danger is transmigration of the soul from one body to another, and only devotional service to the Lord